A few years ago (for my employer at the time), I did some character art for a "run your own casino" Flash game. To my knowledge, the game never surfaced anywhere though. I seem to have done a lot of work on games that never saw the light of day. haha
The client requested male and female avatars with two different skins each. Given that the game was isometric, the avatars had to be constructed (and animated) in all directional views. This called for a LOT of assets.